The Importance of Immune Support for Foals
From pregnancy to the first days after birth, give your foal the best start in life. Explore how colostrum, beta-glucans, antioxidants, and key nutrients build lasting health and strong immunity.
The health and well-being of foals begin long before they are born. The quality of gestation plays a crucial role in their early development, influencing immunity, strength, and resilience.
Why the Mare’s Placenta Matters
Mares have a diffuse epitheliochorial placenta, which is different from some other species. This type does not allow the transfer of immunoglobulins from the mare to the fetus during gestation.
As a result, foals are born immunocompetent—able to mount an immune response—but also immunologically naïve, since they have not yet encountered pathogens or developed specific defenses.
The Role of Colostrum
Right after birth, foals depend entirely on maternal colostrum—the first milk produced by the mare.
Colostrum is rich in immunoglobulins that provide passive immunity, protecting the foal in its first days of life. Beyond immunity, it also delivers essential nutrients for healthy growth.
Beta-Glucans: Natural Immune Boosters
Beta-glucans are polysaccharides extracted from the cell walls of algae, bacteria, cereals, fungi, and yeasts. Their health benefits depend on their molecular structure.
In particular, beta-1,3/1,6-glucan from Saccharomyces cerevisiae yeast has shown positive effects on the immune system in both humans and animals.
Research indicates that β-glucans may stimulate trained immunity—a type of “memory” in the innate immune system—allowing immune cells like macrophages, monocytes, and natural killer cells to respond more effectively when encountering pathogens again.
Oxidative Stress in Newborn Foals
Birth marks a sudden transition from a low-oxygen uterine environment to open-air breathing, which can trigger oxidative stress.
To combat this, antioxidants such as vitamins E and C, and the minerals selenium and zinc, play an essential role in neutralizing free radicals and supporting immune function.
Additionally, glutamine, an important amino acid, serves as fuel for intestinal cells and the immune system.
Supporting a Foal’s Immune Development
A foal’s immune capacity begins forming during gestation and continues to mature throughout its life.
Given the mare’s placenta limitations, colostrum intake in the first hours after birth is critical for long-term health.
By providing targeted nutritional support—rich in antioxidants, essential minerals, and immune-boosting compounds—owners can help foals grow into strong, healthy horses.
